The Locust Street Automotive District in St. Louis, Missouri is a historic district which was listed on the National Register of Historic Places in 2005 and expanded twice, in 2008 and 2016.
The original area included 26 contributing buildings on , at 2914-3124 Locust and 3043 Olive. The first increase extended the district to the west, adding nine contributing buildings on at 3133-3207 and 3150-3202 Locust St. The second increase extended the district to the east, adding 2722-2900 Locust St. and 2727-2801 Locust St.
The district includes works by Preston J. Bradshaw and by Albert B. Groves.