Little Brother or little brother may refer to:
Relationships
Literature
Religion
Organizations
Ships
- , a United States Navy tug in commission from 1917 to 1919
Films and television
Music
Albums
Songs
- "Little Brother," a song from Neil Sedaka's 1974 album Sedaka's Back
- "Little Brother," a song from David Knopfler's 1983 album Release
- "Little Brother", a song from Grizzly Bear's 2006 album Yellow House
- "Little Brother", a song from The Future Sound of London's 1994 album Lifeforms
- "Little Brother", a song by Black Star for the 1999 film The Hurricane
See also
- "Little Bother", a 2022 song by King Princess featuring Fousheé