There are more than 50 completed high-rises in Oklahoma City, most of which stand in the central business district. In the city, 25 buildings stand and taller. The tallest building in Oklahoma City, and in Oklahoma, is the 50-story Devon Tower, which rises above the central business district. Other notable skyscrapers are Chase Tower and First National Center, which stand as the second and third-tallest buildings in Oklahoma City, respectively. Five of the 10 tallest buildings in Oklahoma are located in Oklahoma City.
The Colcord Hotel, Oklahoma City's first skyscraper, was finished in 1909. After oil was discovered in the area, the population of Oklahoma City grew significantly. As a result, the city's skyline expanded, which featured a "race to the top" with the synchronous construction of First National Center and City Place Tower in the central business district. Contemporary skyscrapers began to be built in the north and west sides of Oklahoma City, and later in the downtown area. In 1993, Oklahoma City voters approved the MAPS (Metropolitan Area Projects) program, which featured the construction of several distinct domestic facilities and restorations and expansions of other older ones. It was completed in 2004 and is deemed to be the first program of its kind for a city the size of Oklahoma City.
The Devon Tower, which was completed in 2012, has overtaken the Chase Tower as the tallest building in Oklahoma City with a height of . It has also become the tallest building in the state of Oklahoma, surpassing the BOK Tower in Tulsa. The 50-story building occupies over and had an estimated construction cost of $750 million (USD).
This list ranks Oklahoma City skyscrapers that stand at least tall, based on standard convert measurement; this includes spires and architectural details but does not include antenna masts. The "Year" column indicates the year in which a building was completed.
There are no buildings under construction in Oklahoma City that are planned to rise at least .
This table lists buildings that once held the title of tallest building in Oklahoma City as well as the current titleholder, Devon Energy World Headquarters.