This is a list of miscellaneous agonists of the serotonin receptor subtype 5-HT<sub>2A</sub> (and other 5-HT<sub>2</sub> subtypes to a varying extent) that fall outside the common structural classes. Most agonists at this receptor are either substituted phenethylamine derivatives from the 2C, DOx and 25-NB groups, or substituted tryptamines and related compounds along with more complex derivatives of these such as lysergamides and iboga-type alkaloids. There are however numerous 5-HT<sub>2A</sub> receptor agonists which do not fall within any of these groups, some representative examples of which are listed below. K<sub>i</sub> and EC<sub>50</sub> values vary depending on the assay conditions used and so may not be directly comparable between sources. Many of these compounds have been designed to be non-psychoactive derivatives for medical applications, and it should not be assumed that a compound which acts as a 5-HT<sub>2A</sub> agonist will necessarily be psychedelic in nature.
Analogues of aripiprazole with serotonin 5-HT<sub>2A</sub> receptor agonism and psychedelic-like effects have been reported.