This is a list of notable students, professors, alumni and honorary degree recipients of the University of Santo Tomas in Manila. The following Thomasians were distinguished in various fields such as public service, religion, literary arts, commerce, medicine, among others. The list includes people who have studied at various levels in the university, from elementary up to postgraduate school.
The Royal and Pontifical University of Santo Tomas holds the most number of general championships in the University Athletic Association of the Philippines, 39 senior championships titles in 65 seasons. With a strong athletic program in different sporting events, the university also takes part in various sports leagues such as Filoil Flying V League, Home and Away Invitational League, Collegiate Champion's League, Shakey's V-League and UNIgames; and it continues to produce world-class athletes for the RP National Team.
Through the years, the University of Santo Tomas has conferred the title of Doctor "honoris causa" (honorary degree) upon exemplary men and women who have contributed to the development of Philippine society through a distinct mark of excellence and leadership in their own fields of endeavor.