The episodes of anime series created by Takeshi Konomi are directed by Takayuki Hamana, animated by Trans Arts, and co-produced by Nihon Ad Systems, J.C.Staff, and Production I.G. The anime is an adaptation of Konomi's Prince of Tennis Japanese manga series. The series revolves around a 12-year-old tennis prodigy named Ryoma Echizen, who moves back to his native Japan in order to attend his father's alma mater, Seishun Academy, a private middle school famous for its strong tennis team.
The anime series first aired on the terrestrial Japanese network TV Tokyo from October 10, 2001 to March 30, 2005, airing a total of one-hundred and seventy-eight episodes, which spanned across forty-five DVDs in Japan. In April 2006, an OVA continuation of the anime began to be released on DVD, totaling thirteen episodes across seven DVDs. A second OVA also began being released on DVD on June 22, 2007. It spanned a total of six episodes that are spread across three DVDs, the last of which being released on January 25, 2008. The third and final installment in the National OVA series contains seven episodes spread across four DVDs released from April 25, 2008 to January 23, 2009. The OVAs are animated by Production I.G and Bandai Visual, with the latter also handling the DVD distribution of the OVAs in Japan along with .
Viz Media handled the distribution of the series in North America, where the episodes debuted as streaming media on Viz's and Cartoon Network's joint online broadband service called Toonami Jetstream on July 14, 2006. It first began airing on North American television as part of Toonami's Saturday programming block on December 23, 2006. However, it was removed from Toonami's schedule on June 9, 2007, and was also removed from Toonami Jetstream after episode fifty's broadcast on December 3, 2007. In April 2021, Crunchyroll, then known as Funimation, announced they had licensed the series, and it would stream it on their website with a new English dub. After Funimation was unified under the Crunchyroll brand in 2022, the series joined its namesake streaming service.
As of January 15, 2008, a total of four DVD compilations, containing the first fifty episodes, have been released by Viz Media. All four compilations contain three discs, each containing four episodes, save the final discs of the first two compilations, which contain five episodes.
The 1986 J-pop song Valentine Kiss by Sayuri Kokushà  was covered multiple times by multiple characters in the series. From February 2004 through February 2010, a total of nine different versions were released (seven individually, and the final two together). The first one, featuring the character Keigo Atobe (voiced by Junichi Suwabe) reached #14 on the Oricon charts.
Notes concerning English titles and airdates
Episodes 98âÂÂ115: Training to Defeat Rikkai Jr. High Saga
Episodes 116âÂÂ128: Kanto Tournament Saga - Part V: The Finals - Rikkai Jr. High
Episodes 129âÂÂ135: Recreation Saga - Part II
Episodes 136âÂÂ146: Junior Selection Camp Saga
Episodes 147âÂÂ160: Junior Selection Team vs. U.S. Coast Team Saga
Episodes 161âÂÂ165: Recreation Saga - Part III
Opening & Ending Music
Episodes 166âÂÂ176: Intraschool Rankings Saga - Part III
Episodes 177âÂÂ178: Start of Nationals Arc
Opening & Ending Music
OVA series Episodes 1âÂÂ13: The Nationals Arc
OVA series Episodes 14âÂÂ19: The Nationals Semifinal Arc
OVA series Episode 20âÂÂ26: The National Tournament Finals Arc
OVA series Episode 1âÂÂ4: ~Messages from Past and Future~
OVA series Episode 1âÂÂ4: ~The Times We Shared~
Episodes 1âÂÂ13: ~2nd stringers arc~
OVA series Episodes 1âÂÂ7: The Prince of Tennis II
OVA series Episodes 1âÂÂ10: ~1st stringers arc~
Atobe invites Rikkai to play against Hyotei in an exhibition match. For the third years, this will be their last chance to play with their underclassmen before they graduate.