Sigma Chi is a North American collegiate fraternity. It was established in 1855 at Miami University in Oxford, Ohio, by members who split from the Delta Kappa Epsilon fraternity. The fraternity has 244 active undergraduate chapters and 152 alumni chapters across the United States and Canada. Sigma Chi uses the term "associate chapter" for its colonies.
Following is a list of Sigma Chi collegiate chapters, with active chapters indicated in bold and inactive chapters and institutions in italics.
In the following Sigma Chi alumni chapter list, active chapters are indicated in bold and inactive chapters are in italics.