Chamois Niortais FC was a professional association football club based in Niort, France. The club was founded in 1925 and initially played in regional leagues around western France. It turned professional in 1985 when the team joined Division 2 and two seasons later, they were promoted to the top tier of French football for the first time in their history. Chamois Niortais lost its professional status in the summer of 2009 when the team was relegated from the Championnat National, but regained it three years later following promotion back to Ligue 2. The following list recognises all the players who appeared at least 100 times in the league for Chamois Niortais 1985 until its dissolution in 2025.
The record holder for the highest number of league appearances is midfielder Franck Azzopardi, who played 435 league games for the side between 1989 and 2005. Joël Bossis holds the record for most league goals, scoring a total of 51 during his six seasons with the club.