Line S6 of the Nanjing Metro is a rapid transit line connecting Nanjing and Jurong, Zhenjiang in Jiangsu Province, China. It is long and has a maximum operating speed of . It has opened on 28 December 2021. The line operates with a mixed express and local services using passing loops to allow for express trains to pass local ones.
The line started construction on December 21, 2018. The line is a joint venture between Nanjing Metro and the Jurong local government.