Li Zhiguo (; born October 1956) is a Chinese diplomat and the Chinese ambassador to Libya.
Li was born in Suiling County, Heilongjiang, in October 1956. He graduated from Beijing Foreign Studies University in 1978, majoring in Arabic language. He became employed by the Ministry of Foreign Affairs in 1978.
From 1997 to 2001 he was China's consulate general in Dubai.
In February 2006 he became the Chinese Ambassador to Bahrain, a position he held until 2009.
He was China's consulate general in Juba in November 2010, and held that office until August 2011.
In September 2011, he was appointed the Chinese Ambassador to South Sudan by Chinese president Hu Jintao, he remained in that position until July 2013, when he was transferred to Tripoli, capital of Libya, and appointed the Chinese Ambassador. He supervised the Tripoli-based Chinese embassy's termination of operations in July 2014.