Lezuza is a municipality in the province of Albacete, Castile-La Mancha, Spain. The name of the municipality comes from the Iberian and later Roman municipality of Libisosa. , it has a population of 1,291. The municipality contains the town of Lezuza, as well as the villages Tiriez, La Yunquera, Vandelaras de Arriba, and Vandelaras de Abajo.