Letham is a suburban area of Perth, in the council area of Perth and Kinross, Scotland, approximately west-northwest of the centre of Perth. It borders Tulloch, which is located to the north and northeast. Newhouse Road separates Letham from Hillyland to the west.
Letham lies a short distance east of the A9 and south of the A85 (Crieff Road). The adjacent Hillyland is centred on a hill, which is at its highest point.
Journalist and broadcaster Stuart Cosgrove was born in Letham in 1952 and spent his childhood there.
Football club Letham F.C., established in 1960, is based at Seven Acres Pavilion on Newhouse Road in Letham.
Stagecoach East Scotland'<nowiki/>s route 1 loops between the Mill Street exchange in the city centre, Perth Royal Infirmary, Letham and Tulloch. Route 2 runs the route in reverse.