Lepine Lake is a small lake mostly within Meadow Lake Provincial Park along the course of the Cold River. A section of the south-eastern shore forms part of the border of Big Island Lake Cree Territory Indian reserve. Upstream from Lepine Lake is Pierce Lake while downstream is Lac des ÃÂles. It is about west-northwest of the city of Meadow Lake.
Access to the lake is from River Road in the Indian reserve at the lake's eastern end. Highway 950 runs along the northern shore of Lepine Lake and crosses the Cold River at the western end of the lake.
Fish commonly found Lepine Lake include walleye, northern pike, cisco, white sucker, longnose sucker, lake whitefish, and yellow perch.