Lepidoblepharis williamsi is a species of gecko, a lizard in the family Sphaerodactylidae. The species is endemic to Colombia.
The specific name, williamsi, is in honor of American herpetologist Ernest Edward Williams.
L. williamsi is found in Antioquia Department, Colombia.
L. williamsi may attain a snout-to-vent length (SVL) of . It usually has rust-colored dorsolateral tail stripes.
L. williamsi is oviparous.