Le Moutherot () is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France.
The commune lies from Besançon, Dole, and Gray between the rivers Ognon and Doubs.
On a top of a hill, the village offers a view on fields, forests. In bright weather Mont Blanc, the Mount Poupet, and the "Ballon of Alsace" can be seen.