Lauren De Crescenzo (born September 3, 1990) is an American professional racing cyclist. After a dedicated collegiate career, De Crescenzo won the 2021 Unbound Gravel race and placed as a runner-up in 2022. She overcame a traumatic brain injury from cycling to complete graduate school studying epidemiology and win races as a professional cyclist.
De Crescenzo rode in the women's team time trial at the 2015 UCI Road World Championships.
Her college career included bronze medals in the 2018 USA Cycling Collegiate National Championship Road Race and Individual omnium, as well as gold in the 2019 Individual time trial. On May 31, 2020, De Crescenzo set the women's everesting world record, ascending Hogpen Gap in Blairsville, Georgia 24 times in nine hours and fifty-seven minutes. Her ride covered 111 miles with an average climb gradient of 9.83%. In June 2021, she won the 2021 Unbound Gravel 200 in 12:06:49. In 2022, she placed second in the race.
In 2023, De Crescenzo has continued to race on gravel roads and engage with sponsors on endorsement deals.
De Crescenzo is a graduate of Emory University. During her first professional racing season in 2016, she suffered a traumatic brain injury (TBI) following a bike crash, after which she was placed in a medically induced coma for six days. De Crescenzo had a lengthy rehabilitation period in Colorado, after which she could relearn basic tasks and return to bicycle racing and graduate school. Following her recovery, De Crescenzo has gone on to finish graduate school, complete a fellowship at the Centers for Disease Control, and win more bike races.