Larkana Junction Railway Station (, ) is a railway station located in Larkana, Sindh, Pakistan. It was built in 1891. The station is staffed and has a booking office.
The routes are Larkana from linked to Karachi, Lahore, Quetta, Peshawar, Rawalpindi, Nowshera, Hyderabad, Sibi, Sukkur, Attock, Mianwali, Dadu, Rahim Yar Khan, Shikarpur, Kotri, Rohri, Nawabshah and Jacobabad .