Lysimachia () is a lake in Aetolia-Acarnania, western Greece. Its area is 13.2 km<sup>2</sup>, its depth is around 9 m. It is fed by the small river Ermitsa, and by a canal that connects the lake with the larger Lake Trichonida to its east. Its outflow is the river Dimikos, which drains into the river Acheloos. The city of Agrinio lies 6 km to the northeast.