Lysophosphatidic acid receptor 2 also known as LPA<sub>2</sub> is a protein that in humans is encoded by the LPAR2 gene. LPA<sub>2</sub> is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca<sup>2+</sup> mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.
LPAR2 has been shown to interact with TRIP6.
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