L-threonate 3-dehydrogenase

In enzymology, L-threonate 3-dehydrogenase () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are threonic acid and oxidised nicotinamide adenine dinucleotide (NAD⁺). Its products are 3-dehydro-L-threonic acid, reduced NADH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donors with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is L-threonate:NAD⁺ 3-oxidoreductase. Other names in common use include threonate dehydrogenase, and L-threonic acid dehydrogenase. This enzyme participates in ascorbate and aldarate metabolism.

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