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L-cysteate sulfo-lyase

The enzyme <small>L</small>-cysteate sulfo-lyase (EC 4.4.1.25) catalyzes the reaction

<small>L</small>-cysteate + H<sub>2</sub>O = hydrogensulfite + pyruvate + NH<sub>3</sub> (overall reaction)
:(1a) <small>L</small>-cysteate = hydrogensulfite + 2-aminoprop-2-enoate
:(1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)
:(1c) 2-iminopropanoate + H<sub>2</sub>O = pyruvate + NH<sub>3</sub> (spontaneous)

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is <small>L</small>-cysteate bisulfite-lyase (deaminating; pyruvate-forming). Other names in common use include <small>L</small>-cysteate sulfo-lyase (deaminating), and CuyA.

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