Kleidonia () is a village and a community in the municipality of Konitsa, Ioannina regional unit, Epirus, Greece. The community includes the village Kalyvia. The Greek National Road 20 (Ioannina - Konitsa - Kozani) passes through Kalyvia. It is situated on the right bank of the river Voidomatis, a tributary of the Aoos.
Two prehistoric locations have been found near Kleidonia:
In these two caves there are archaeological remains that date back to 20,000 and 12,000 years ago, in the later period of the Paleolithic Era in Greece.