Khlong Maha Nak (, ) is one of five khwaengs (subdistricts) of Pom Prap Sattru Phai District, Bangkok.
It is named after the Khlong Maha Nak canal that flows through and bisects the area.
Roads neighboring this subdistrict include (from the north clockwise): Lan Luang, Worachak, Bamrung Mueang, Krung Kasem.
Khlong Maha Nak, Khlong Phadung Krung Kasem, and Khlong Saen Saep are main watercourses. The Khlong Phadung Krung Kasem canal serves as the boundary between Si Yaek Maha Nak Subdistrict, Dusit District, and Rong Mueang Subdistrict, Pathum Wan District.
Total population of 9,482 people (4,473 men, and 5,009 women) most of the people are Muslims live in Masjid Maha Nak's neighbourhood by the Khlong Maha Nak.