Khargone Lok Sabha constituency () is one of the 29 Lok Sabha (parliamentary) constituencies in the Indian state of Madhya Pradesh state in central India. This constituency came into existence in 1962. It is reserved for the candidates belonging to the Scheduled Tribes and covers the entire Barwani district and part of Khargone district.
Presently, Khargone Lok Sabha constituency comprises the following eight Vidhan Sabha segments:
^ by poll