Muhammad Khairu Azrin bin Khazali (born 13 July 1991) is a Malaysian professional footballer who plays for Malaysia A2 Amateur League club ACEIO. Khairu Azrin mainly plays as a defensive midfielder.
In November 2016, Khairu Azrin signed with 2016 Premier League champions Melaka United. On 27 January 2017, he made his debut and scored one goal for during the first league match against Selangor in Selayang Stadium. That match end up with a draw 1âÂÂ1.
In June 2017, during second window transfer, Khairu Azrin returned to PKNS after just 6 months playing for Melaka United. It was agreed that S. Sivanesan would replace him at Melaka United.
Khairu Azrin joined Felda United F.C. for the 2018 Malaysia Premier League, and the team won the league.
In the 2019 season, Khairu Azrin joined Terengganu, alongside Syamim Yahya from Felda United.
In 2020, he moved to another Malaysia Super League club, Penang. He helped them to win the 2020 Malaysia Premier League, thus securing their promotion to the 2021 Malaysian Super League.
On 1 December 2021, Khairu Azrin agreed to join Malaysia Super League side Kedah Darul Aman F.C.
In the 2023 season, Khairu Azrin joined Kelantan United.