Khairpur or Khayrpur may refer to:
- Khairpur, a city in Sindh, Pakistan
- Khairpur District, which has Khairpur city as its capital
- Khairpur Division, former division of West Pakistan later Sind province
- Khairpur (princely state), a former princely state of Pakistan and British India, abolished in 1955
- Khairpur, Badin, a village in Sindh, Pakistan
- Khairpur, Chakwal, Punjab, Pakistan
See also