The Keesee House is a historic house at 723 Arkansas Street in Helena, Arkansas. It is a -story wood-frame structure, built in 1901 for Thomas Woodfin Keesee, the son of a local plantation owner. It is an excellent local example of transitional Queen Anne-Colonial Revival architecture, exhibiting the irregular gable projections, bays and tower of the Queen Anne, but with a restrained porch treatment with Ionic columns. The exterior is sheathed in a variety of clapboarding and decorative shingling, and there are wood panels with carved garland swags.
The house was listed on the National Register of Historic Places in 1983.