Kattakurgan District () is a district of Samarqand Region in Uzbekistan. The capital lies at the town Payshanba. It has an area of and its population is 276,700 (2021 est.).
The district consists of 8 urban-type settlements (Payshanba, Suv hovuzi, Mundiyon, Polvontepa, Qoradaryo, Vayrat, Yangiqoûrgûoncha, Kattaming) and 11 rural communities.