Kateh Sar-e Khomam Rural District () is in the Central District of Khomam County, Gilan province, in Iran. Its capital is the village of Kateh Sar.
At the time of the 2006 National Census, the rural district's population (as a part of the former Khomam District in Rasht County) was 11,757 in 3,416 households. There were 11,406 inhabitants in 3,778 households at the following census of 2011. The 2016 census measured the population of the rural district as 10,463 in 3,687 households. The most populous of its 12 villages was Kalachah, with 1,926 people.
In 2020, the district was separated from the county in the establishment of Khomam County, and the rural district was transferred to the new Central District.