Karen Andrea Medina Vásquez (born 10 May 1982) is a Chilean politician who serves as deputy.
She was born in Nacimiento on 10 May 1982. She is the daughter of Mario Alcides Medina Medina and Lidia del Carmen Vásquez Miranda.
She completed her secondary education at Juanita Fernández Solar High School in the commune of Angol.
She is a former member of the Party of the People (PDG). She has twelve years of experience as a trade union leader representing education assistants.
In the parliamentary elections held on 21 November 2021, she was elected to the Chamber of Deputies of Chile representing the 21st electoral district of the BiobÃÂo Region. The district comprises the communes of Alto BiobÃÂo, Antuco, Arauco, Cabrero, Cañete, Contulmo, Curanilahue, Laja, Lebu, Los ÃÂlamos, Los ÃÂngeles, Lota, Mulchén, Nacimiento, Negrete, Quilaco, Quilleco, San Rosendo, Santa Bárbara, Tirúa, Tucapel and Yumbel. She was elected representing the Party of the People, obtaining 10,066 votes, equivalent to 5.13% of the valid votes cast.
She resigned from the Party of the People on 1 August 2024.
She sought re-election in the parliamentary elections of 16 November 2025 for the same district, running as an independent candidate on a Christian Democratic Party ticket within the Unity for Chile coalition. She was not elected, obtaining 13,633 votes, equivalent to 3.49% of the valid votes cast.