Potassium channel subfamily K member 6 is a protein encoded by the KCNK6 gene in humans.
This gene encodes K<sub>2P</sub>6.1, a member of the superfamily of potassium channel proteins containing two pore-forming P domains. K<sub>2P</sub>6.1, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid and inhibited by internal acidification and volatile anaesthetics.