Juan Manuel López vs Rafael Márquez, billed as Puerto Rico vs. Mexico, was a professional boxing match contested on November 6, 2010, for the WBO featherweight championship. The fight was highly anticipated due to the history of competition between Mexican boxers and those from Puerto Rico.
The fight was originally scheduled for September 18 but postponed due to an injury Marquez sustained on his right thumb. The fight was rescheduled for November 6, which was Lopez's second defense of his WBO title and was broadcast on Showtime.
Marquez lost the fight in the 8th round by TKO after he was unable to continue due to a shoulder injury. Marquez had chosen to proceed with the bout even though he suffered with a right shoulder injury before the contest because he did not wish to cause a second delay. It was later revealed that Marquez had suffered a hairline fracture in his right shoulder blade during the fight and would require six months to recover from the injury. Despite the loss Marquez expressed his eagerness to face Lopez in a rematch.
Lopez defeated Marquez via technical knockout in the eighth round. Marquez was unable to continue following the eighth round citing a shoulder injury.
Johnson defeats Green via knockout in the eighth round.
Attah defeated Quintero via knockout in the second round.
Magdaleno defeated Campos via technical knockout in the fourth round.
Bey Jr defeated Cruz via unanimous decision (60-53, 59-53, 59-53).
Arroyo defeated Grajeda via technical knockout in the first round.
Lenk defeated Escobar via unanimous decision.
Magdaleno defeated Salazar via technical knockout in the first round. This was Magdaleno's professional debut.