Joseph Mopeli Sephamola O.M.I., (born 14 March 1960) is a Lesothan Roman Catholic prelate who is the Bishop of the Roman Catholic Diocese of Qacha's Nek, Lesotho. He is a member of the Order of the Missionary Oblates of Mary Immaculate. He was appointed bishop on 19 June 2013 by Pope Francis. He was installed at Qacha's Nek in September 2013.
He was born on 14 March 1960 at Tsoelike, Qacha's Nek District, Diocese of Qacha's Nek, in Lesotho. He attended the St. Augustine's Major Seminary in Roma, Lesotho from 1984 until 1989. In 2000 he took a short course at the Oblate School of Theology. He studied at St Anselm's College in Merseyside, England from 2002, graduating from there with a Diploma in Human Growth and Development in 2003. In 2019, he studied at the University of Kwazulu Natal, graduating with a Master's degree in Spirituality (Theology).
He professed to be a member of the Oblates of Mary Immaculate (OMI) on 6 January 1984. On 25 January 1989 he took his solemn vows as a member of that Roman Catholic Order. He was ordained a priest of the same Order on 27 April 1991.
Following his ordination, he served in various roles including as:
On 19 June 2013 Pope Francis appointed him bishop of the Roman Catholic Diocese of Qacha's Nek, a suffragan of the Metropolitan Archdiocese of Maseru. He was consecrated and installed on 21 September 2013 at Qacha's Nek, Diocese of Qacha's Nek, Lesotho.
The Principal Consecrator was Archbishop Gerard Tlali Lerotholi, Archbishop of Maseru assisted by Archbishop Jabulani Adatus Nxumalo, Archbishop of Bloemfontein and Bishop Augustinus Tumaole Bane, Bishop of Leribe.
(17 July 1981 - 17 July 2010)