Jo Gilis (born 5 February 2000) is a Belgian professional footballer who plays as an attacking midfielder or a winger for Houtvenne.
Gilis played his first match for OH Leuven on 14 April 2018, coming on as a substitute for Nikola Storm in a 0-2 win at Waasland-Beveren.
Gilis has two older sisters, Nele Coll (née Gilis) and Tinne Gilis, who are both professional squash players representing Belgium.