Prince Jerzy Dominik Lubomirski (; 1665–1727) was a Polish noble (szlachcic).
He was the son of Grand Marshal and Hetman Jerzy Sebastian Lubomirski and Barbara Tarà Âo. In 1695 he married Urszula of Altenbockum. The marriage was dissolved by the Pope and in c. 1710 he married Magdalena Tarà Âo, daughter of , Voivode of Lublin.
He was Podstoli of the Crown since 1695, Podkomorzy of the Crown since 1702, voivode of Kraków Voivodeship since 1726 and owner of Poà Âonne, Janowiec and Lubomla.
He was also the Starost of Olsztyn, Kazimierz Dolny and Lipno.