Jay Clayton

Jay Clayton may refer to:

• Jay Clayton (attorney) (born 1966), American lawyer and United States attorney for the Southern District of New York
• Jay Clayton (critic) (born 1951), American literary critic
• Jay Clayton (musician) (1941–2023), American jazz vocalist and educator
• Jay Clayton (wrestler) (1941–2005), American professional wrestler
• Jay Clayton, English musician and songwriter in the band Crywank