National Route 122 is a national highway of Japan connecting Nikkà Â, Tochigi and Toshima, Tokyo in Japan, with a total length of .
A section of National Route 122 in Midori in Gunma Prefecture is a musical road.
Route 122 was originally designated on 18 May 1953 from Maebashi to Mito. This was redesignated as Route 50 on 1 April 1963 and the current Route 122 was designated the same day.