Jane Ayiyem (born 19 October 1997) is a Ghanaian international footballer who plays as a forward for the Ghana women's national football team. She competed for Ghana at the 2018 Africa Women Cup of Nations, playing in three matches.
In 2012, 2013, and 2014 Sports Writers Association of Ghana "SWAG" Awards, Ayieyam won the best Female Footballer of the year and was also the 2012 female top scorer with 18 goals.