Jan-Hendrik Wessels (born 8 May 2001) is a South African professional rugby union who is a player for the in the United Rugby Championship, in the Currie Cup and the South African national team. His regular position is hooker or loosehead prop.
Wessels was named in the squad for the Super Rugby Unlocked competition. He made his debut for the Bulls in Round 2 of the 2020 Currie Cup Premier Division against the .