James Smyth may refer to:
- Sir James Smyth (English MP) (c. 1621âÂÂ1681), English member of parliament for Exeter and Camelford
- Sir James Smyth, 1st Baronet (c. 1686âÂÂ1717), sheriff of Sussex 1714âÂÂ15
- James Smyth (Irish MP) (c. 1716âÂÂ1771), Irish member of parliament for Antrim and Dundalk
- James Smyth (priest) (1683âÂÂ1799), Anglican priest in Ireland
- James Carmichael Smyth (physician) (1742âÂÂ1821), Scottish medical writer and physician to King George III
- Sir James Carmichael-Smyth, 1st Baronet (1779âÂÂ1838), his son, British colonial administrator
- James Adger Smyth (1837âÂÂ1920), mayor of Charleston, South Carolina
- Red Smyth (James Daniel Smyth, 1893âÂÂ1958), American baseball player
- James G. Smyth (fl. mid-20th century), American politician
- Jimmy Smyth (hurler) (1931âÂÂ2013), Irish hurler
- James Smyth (rugby union), Irish international rugby union player
See also