James or Jimmy Milne may refer to:
- James Milne (cricketer) (born 1961), New Zealand cricketer
- James Milne (railway manager) (1883âÂÂ1958), GWR General Manager
- James Milne (sport shooter) (died 1958), British sports shooter; see Great Britain at the 1908 Summer Olympics
- James Milne, solo artist and bassist for Okkervil River, known as Lawrence Arabia
- James Milne, bassist for Cornershop
- James Milne (mathematician) (born 1942), New Zealand mathematician
- James M. Milne (1850âÂÂ1903), principal of the State University of New York at Oneonta
- James F. Milne (born 1950), Vermont business and political figure
- James Robert Milne (died 1961), Scottish physicist
- Jimmy Milne (footballer, born 1911) (1911âÂÂ1997), Scottish football player and manager
- Jimmy Milne (Australian footballer) (1898âÂÂ1961), Australian footballer for St Kilda
- Jimmy Milne (trade unionist) (1921âÂÂ1986), STUC General Secretary
- James Milne (high jumper) (born 1919), American high jumper, 1942 NCAA runner-up for the Michigan State Spartans track and field team
- James Milne (priest) Precentor of St Paul's Cathedral