The Isuzu Giga () is a line of heavy-duty commercial vehicles produced by Isuzu since 1994. Outside of Japan, the line is known as the Isuzu C/E series and Isuzu S&E series and was formerly known as the Isuzu Heavy-Duty Truck'. Between 1994 and 2016, it was also sold in South America (under the Chevrolet brand as Chevrolet C/E series).
The Isuzu Giga heavy-duty truck was first introduced in 1994 as the successor to the Isuzu 810. The early models featured multiple body types (box truck, tractor trailer, dump truck), new high GVW options (22t and 25t), and advanced design elements such as bumper-mounted headlights, which later became common in the industry. Several trim levels were offered, ranging from basic to luxury. Over the years, the Giga went through multiple updates that brought design refreshes, safety improvements, and regulatory compliance. In 1997, it became the first large truck line to include SRS airbags and HID headlights as standard safety features. Engine options evolved from V-type engines to more efficient straight-six and turbocharged engines, especially to meet stricter emission and noise regulations in the 2000s. Between 2000 and 2007, further updates focused on emissions compliance, safety standards, exterior redesigns (such as grille and bumper changes), and improved technology. Advanced features like radar-based distance warning and cruise control were introduced by 2007. By this time, older configurations (such as low cab and off-road cabs) were phased out.
Between 2007 and 2010, the Isuzu Giga received updates focused on safety, efficiency, and regulatory compliance. In 2007, electronic stability control (IESC) was added to tractor models, older engine types were discontinued, and a collision damage mitigation braking system was developed. By 2009, exterior components like mirrors and turn signals were redesigned to meet international regulations, and a side-monitoring feature was added to the driver assistance system.
In 2010, a major update introduced new emissions technology (SCR + DPD), standardized the engine lineup to the 6UZ1, improved cooling and lighting through cab redesign, added a new 16-speed transmission for dump trucks, and updated wheel standards.
The second-generation Isuzu Giga was unveiled at the 2015 Tokyo Motor Show and launched with a full model change. The new model introduced a redesigned cab shared with Forward and Elf trucks, improved aerodynamics, updated interior with digital displays and steering controls, multiple cab configurations, and enhanced comfort. The 6UZ1 engine continued with efficiency upgrades, alongside improved transmissions and fuel-saving technologies such as Smart Glide. Advanced safety systems were added, including improved pre-crash braking, lane departure warning, and driver support technologies. Fleet management systems (MIMAMORI and PREISM) were also enhanced.
From 2015 to 2018, updates included the introduction of CNG, improved tractor models, new engines (including the 6NX1), better fuel efficiency, compliance with newer emissions regulations, and LED lighting upgrades. Special editions were released, such as the 80th Anniversary model. Between 2019 and 2021, safety became a major focus, with pedestrian and cyclist detection systems, blind spot monitoring, driver monitoring, adaptive cruise control, lane keep assist, and the Emergency Driving Stop System (EDSS) were added. Comfort improvements included higher roofs and premium seating. Monitoring features expanded to include tire pressure, battery status, and safety reporting.
In 2025, the Giga became the first heavy-duty truck in Japan to include a wheel detachment warning system as standard on all models, alongside further strengthened safety technologies.
With the full model change, the symbol at the end of the model has been changed from the original Giga QKG-CYL77 A to QPG-CYL77 B, for example, in 6x2.
As of 2022 the second generation Giga has launched in Japan, China and Malaysia.
The UD Quon-based model was introduced in March 2023.
"Classification" in the table below indicates the two digits of the three letters of the vehicle model code (C ** or EX * above).