Istanbul Girls' High School (: 1850-1988) was the first state established girls' school in the Ottoman Empire.
The school was inaugurated on , by Sadrazam Mustafa Reshid Pasha, one of the architects of the Tanzimat reforms, in a building donated by Bezmiâlem Sultan, mother of Sultan Abdulmejid I. At the beginning, it was a secondary school ().
During most of the republican period in Turkey, the school was known under the name ðstanbul Kñz Lisesi, but always related to its founding mother Bezm-i Alem, whose name it carried officially as Bezm-i Alem Sultanisi for about a decade until 1924, when it was renamed.
The school could not be spared from a spree of closing (or turning into a mixed gender school), similar to what other girls-only schools also experienced in Turkey in the early 1980s. It ceased receiving new students in 1984, had its final graduates in , and then closed down. At its closure, its building became CaÃÂaloÃÂlu Anatolian High School.