Isoorientin (homoorientin) is a flavone, a chemical flavonoid-like compound. It is the luteolin-6-C-glucoside.
Isoorientin can be isolated from the passion flower, Vitex negundo, Terminalia myriocarpa, the Açaàpalm, and Swertia japonica.
Isoorientin has been studied for its potential pharmacological activity. Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycaemic component in Gentiana olivieri. Studies also showed that isoorientin is a potential neuroprotective compound against Alzheimer's disease.