The Isle of Man competed at the 2022 Commonwealth Games in Birmingham, England between 28 July and 8 August 2022. Having made its Games debut in 1958, it was the Isle of Man's seventeenth appearance at the Games.
Cyclist Mark Cavendish and swimmer Laura Kinley were the country's flagbearers during the opening ceremony.
The Games marked the first time since 2002 that the Isle of Man failed to win any medals.
The following is the list of number of competitors participating at the Games per sport/discipline.
Two athletes were selected on 14 September 2021; a further two were added on 25 January 2022 and three more on 5 May 2022.
One player was selected on 3 May 2022.
Two boxers were selected on 3 May 2022.
Eight cyclists were selected on 14 September 2021; a further three were added on 25 January 2022 and two more on 5 May 2022.
One gymnast was selected on 25 January 2022.
One powerlifter was selected on 3 May 2022.
Two swimmers were selected on 14 September 2021; a further two were added on 25 January 2022 and two more on 5 May 2022.
A seventh swimmer was added on 22 June 2022.
One triathlete was selected on 25 January 2022, followed by a second on 2 June 2022.