Iset or ISET may refer to:
- Iset, an Ancient Egyptian name
- Isis, a goddess in Ancient Egyptian religious beliefs
- Iset (village), a village in Kachugsky District, Irkutsk Oblast, Russia
- Iset (river), a river in Russia rising in the Ural Mountains and flowing east into the Tobol River
- International Solar Electric Technology is a solar power company
- International School of Economics at Tbilisi State University, a graduate school of economics in Tbilisi
- Inner sphere electron transfer, a mechanism of electron transfer in inorganic chemistry
- Institut Supérieur des ÃÂtudes Technologiques, or Higher Institute of Technological Studies, a class of universities in Tunisia
- ISET Test, a diagnostic blood test that detects circulating tumor cells in a blood sample