Ise Ekiti (; , also Ise) is a city in Ekiti State, Nigeria. It is the traditional home of Akinluaduse, also known as Akinluse by the inhabitants of the city. Akinluse was a great warrior in the ancient Oyo Empire. Ise-Ekiti is the headquarters of the Ise/Orun Local Government Area, along with Orun. Its geographic coordinates are . Ise ekiti is divided into three quarters namely; Oraye, Odo Ise and Erinwa. The Arinjale of Ise-Ekiti is Oba Ayodele Ajayi Aweloye II. .
As of 2007 Ise local government had an estimated population of 204,022.