Isabel Sanford's Honeymoon Hotel is an American sitcom that was broadcast in first-run syndication in January 1987. The stripped series, airing five days a week, was created to showcase Isabel Sanford's comedic skills, but it failed to attract an audience and was quickly cancelled. The title of the series may have likely been inspired by an episode from the tenth season of The Jeffersons called "Honeymoon Hotel".
Isabel Scott is a divorcee who runs Isabel's Honeymoon Hotel, a once profitable but now debt-ridden inn. Accompanying Isabel are her ex-husband K.C., her niece Jolie, her assistants Martha and Carlton, Mel the bartender, and Agnes the chambermaid.
Casey Kasem was the program's announcer. Guest stars included Lydia Cornell, Kelly Monteith, David Lander, and Marcia Wallace.
It was produced by De Laurentiis Entertainment Group in association with Fred Silverman. The plan was to have 100 new episodes made by the fall of 1987.
It debuted as a "pilot week" on several stations in January 1987. However, DEG went bankrupt before production was to fully start, thereby cancelling the show.