Isaac Donkor (born 15 August 1995) is a Ghanaian professional footballer who plays as a centre-back for Qatari Second Division club Mesaimeer.
Donkor started his professional career with Inter. He made his debut for Inter on 22 November 2012 against FC Rubin Kazan in the Europa League. Donkor, on 13 July 2015 Bari on loan. Donkor, on 6 July 2016 Avellino on loan. Donkor, in January 2017 he was transferred to Cesena on loan. Donkor joined Cesena on a permanent basis on 24 July 2017.
Donkor signed a 3-year contract with Romanian club Universitatea Craiova in July 2018.
On 2 September 2019, he signed a contract with Austrian club Sturm Graz for one year with an extension option.
Donkor joined Turkish club Adanaspor in September 2020.
He signed a 2-year contract with Sakaryaspor in June 2022.
Donkor joined Adanaspor on 29 August 2024.