Irune Murua Cuesta (born 23 April 1986) is a Spanish retired football forward who played for Athletic Bilbao of Spain's Primera División.
Murua was a member of the Spanish team that won the 2004 Under-19 European Championship, where she scored two goals in the two first matches against Switzerland and Finland.
In May 2017, she announced her retirement from professional football.
Irune Murua is the daughter of former footballer Andoni Murua.